Epigenetics of Male Fertility: Effects on Assisted Reproductive Techniques

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Epigenetics and assisted reproductive technology.

During gametogenesis, the female and male germ cells undergo a process whereby imprinting marks are erased from the genome. During the later stages of germ-cell development, the methylation marks of the female and male germ lines are re-established. A second phase of demethylation of the genome occurs at the time of fertilization, and during development of the early embryo. Assisted reproductiv...

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In recent years, male fertility has changed due to the effects of environmental, health and lifestyle factors and the infertility rate has increased, to the extent that male fertility may be affected by extreme heat, exposure to pesticides, radiation, substances Changes in radioactivity, lifestyle, stress and occupation. In the environment, there are ionizing and non-ionizing rays whose effect...

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Effects of Pesticides on Male Reproductive Functions

Exposure to pesticides could be one of the contributing cause to the falling sperm counts and rising levels of male infertility. Adverse effects of pesticides in the environment first received widespread attention in the 1960s. However, only recently it has been postulated that long term, low exposure of these chemicals are increasingly linked to human health effects such as immuno-suppression,...

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Effects of carbamazepine on male reproductive hormones

  Background :Reproductive endocrine disorders and sexual dysfunction are common among men with epilepsy. We investigated sexual hormone serum levels among men with newly diagnosed epilepsy, before starting any antiepileptic drug (AED), and then after starting carbamazepine (CBZ), to determine the role and effects of epilepsy versus CBZ in creating reproductive endocrine disorders.   Methods : ...

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Heterotopic Pregnancy after Assisted Reproductive Techniques

Heterotopic pregnancy (HP) is the simultaneous occurrence of intra- and extrauterine pregnancies. It is a rare event in spontaneous pregnancies with an incidence of less than 1:15000 however the frequency has increased to 1% in accordance with the widespread use of assisted reproductive techniques (ART). The pre-operative diagnosis of this condition is generally difficult and it would be life t...

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ژورنال

عنوان ژورنال: The World Journal of Men's Health

سال: 2019

ISSN: 2287-4208,2287-4690

DOI: 10.5534/wjmh.180071